ORIGINAL  
Niger J Paed 2015; 42 (2): 98 –102  
Sadoh WE  
Sadoh AE  
Eki-Udoko FE  
Parental contribution to over  
prescription of antibiotics for sore  
throat in children  
DOI:http://dx.doi.org/10.4314/njp.v42i2.5  
Accepted: 17th November 2014  
Abstract: Introduction: Antibiot-  
ics are often prescribed by physi-  
cians for sore throat in children  
because of the danger of post  
streptococcal complications. The  
role of the parents in over  
prescription of antibiotics is less  
well known.  
Objective: To evaluate the knowl-  
edge, attitudes and practice of  
parents to antibiotic prescription  
for childhood sore throat.  
Methods: The subjects were par-  
ents who brought their children to  
the out-patient clinics of a tertiary  
hospital. Their knowledge, atti-  
tude and practice of antibiotics  
prescription for sore throat in chil-  
dren were evaluated with the aid  
Respondents were aged 20 to 64  
years. While 54.0% of respondents  
believed sore throat may resolve  
without antibiotics, 69.4% also felt  
that every child with sore throat  
should receive antibiotics. Some  
57.2% of respondents will request  
for antibiotic. More respondents  
with secondary (59.0%) and terti-  
ary (56.6%) levels of education  
compared to primary (20.6%) level  
would not request for antibiotics, P  
= <0.001. 42% will not be satisfied  
with a physician who does not  
prescribe antibiotics.  
Conclusion: This study demon-  
strated parental irrational demand  
for antibiotic for sore throat in  
children. This attitude was more in  
less educated parents. Education of  
the parents about the aetiology and  
rational antibiotic use of sore  
throat in children will mitigate this  
behavior.  
(
)
Sadoh WE  
Sadoh AE, Eki-Udoko FE  
Department of Child Health,  
University of Benin Teaching Hospital,  
PMB 1111, Benin City,  
Nigerian.  
E-mail: sadohehi @yahoo.com  
of  
a questionnaire. Responses  
were analyzed with IBM-SPSS  
version 20.0. The responses were  
presented in simple percentages  
while differences in proportions  
2
were tested with χ test.  
Results: There were 309 respon-  
dents studied, of which 264  
Keywords: Sore throat; antibiotic  
over prescription; knowledge;  
attitude, parents  
(
85.4%) were mothers.  
6
,7  
Introduction  
been demonstrated in earlier reports . Thus the avail-  
able sensitive antiobiotics are the more expensive newer  
medicines, which are beyond the reach of most Nigeri-  
ans. It is thus imperative that efforts are made to prevent  
antibiotic resistance in our environment.  
Pharyngitis or sorethroat is a common childhood illness  
which presents with cough fever and pain . When  
caused by group A β haemolytic streptococcus, it may  
1
result in rheumatic fever and acute glomerulonephritis  
2
after the acute illness . Rheumatic heart disease which is  
The demand by parents on physicians to prescribe an  
antibiotic for sore-throat in their children has also been  
documented as contributing to the unnecessary antibiotic  
a debilitating chronic sequala of rheumatic fever may  
also occur . In an effort to prevent these late complica-  
tions, physicians often prescribe antibiotics for sore-  
2
3
prescription for sorethroat . Whilst the role physicians’  
throat with or witho,4ut establishing if the causative or-  
play in over prescription of antibiotic has been identified  
in Nigeria , there is paucity of literature on the role of  
3
4
ganism is bacterial . However it is well known that  
majority of sore-throat are caused by viruses rather than  
bacteria and as such does not require antibiotics in most  
cases . In a previous study conducted in the same study  
the Nigerian parents. In this study, we evaluated the  
knowledge and attitude of the parents of children attend-  
ing the paediatric clinics and wards on treatment of sore-  
throat, antibiotic prescription and attitude to their physi-  
cians.  
5
locale, it was found that physicians tended to misuse and  
3
over-prescribe antibiotics for sore-throat .  
The unnecessary antibiotic prescription for sore-throat  
contributes to antibiotic resistance. The resistance of  
various organisms to the commonly used antibiotic has  
9
9
Methods  
children who were at least 5 years old. Of which 143  
(70.1%) had had sore-throat in the past.  
The respondents were parents of children visiting the  
paediatric out-patient clinics and children’s emergency  
room of the University of Benin Teaching Hospital,  
Benin City. A convenience sample size of 320 respon-  
dents was consecutively recruited from the wards and  
clinics, over a period of six months July to December  
Knowledge of treatment of sore-throat  
Of the 309 respondents in this study, 272(88.0%)  
thought that sore-throat should be treated; of these, 262  
(84.8%) thought it should be treated to ease discomfort,  
103 (33.3%) to prevent spread to other children and 186  
(60.2%) to prevent complications (some respondents  
gave multiple responses).  
Most respondents 213(69.4%) felt every child with sore-  
throat should have an antibiotic, 166(54.0%) believed  
sore-throat may resolve without antibiotics while 264  
(86.6%) would take their child to see a doctor to prevent  
potential complications. The responses of the respon-  
dents to other knowledge related questions are presented  
in table 1.  
2
013. The knowledge and attitude of respondents to  
antibiotic prescription for sore-throat in their children  
was evaluated in this study using a semi-structured inter-  
viewer administered questionnaire. The questionnaires  
were administered by four trained interviewers who are  
medical doctors. The questionnaire was pre-tested on 40  
respondents to collate the various types of responses and  
ensure there is consistency in the understanding of ques-  
tions and their responses by respondents.  
The questionnaire is divided into two sections. The first  
section sought for information on biodata, the educa-  
tional level and socio-economic statuses of the respon-  
dents. The socio-economic class (SEC) of the respon-  
dents was determined using the method described by  
Parental attitudes to antibiotics for sore-throat  
Some 174(57.2%) respondents will request for an antibi-  
otic for their child’s sore-throat while 129(42.2%) will  
not be satisfied with a doctor who does not prescribe an  
antibiotic for their child’s sore-throat. Seventy (22.7%)  
respondents would change their doctors for not prescrib-  
ing an antibiotic. Table 1.  
8
Olusanya et al . Respondents were also asked if they  
thought sore-throat should be treated and the reasons  
they felt it should be treated.  
The second section evaluated the knowledge on antibi-  
otic use in sore-throat, potential complications from sore  
-
throat and attitude towards their physicians’ prescrip-  
tion or non-prescription of antibiotic for their children’s  
sore-throat. The responses were organized into a 3  
likert’s scale consisting of agree, not sure and disagree  
to the questions.  
Table 1: Parents knowledge and attitude towards antibiotic  
prescription for sore-throat  
Questions  
n = number of responses  
Responses  
not sure  
Agree  
Disagree  
Every child with ST should have antibiotic  
(
n = 307)  
213(69.4) 40(13.0)  
166(54.0) 65(21.2)  
54(17.6)  
76(24.8)  
Statistical analysis  
ST may resolve without antibiotic (n = 307)  
See a doctor to prevent potential complication  
from ST? (n=305)  
Would you request for antibiotic for your child  
with ST? (n= 304)  
Satisfied with a doctor who does not prescribe  
antibiotic for ST? (n=306)  
Would you see another doctor to get antibiotic  
for ST? (n = 304)  
Would you change your doctor for not  
prescribing antibiotic for ST?(308)  
Is your child receiving too much antibiotic when  
prescribed for ST? (n=302)  
264(86.6) 17(5.6)  
174(57.2) 43(14.1)  
24(7.8)  
The responses were coded and entered into a spread  
sheet using IBM-SPSS version 20.0 Chicago IL. Analy-  
sis was done with the same tool. The responses of the  
different categories of respondents were presented in  
simple percentages. The differences in proportion were  
87(28.6)  
127(41.5) 50(16.3) 129(42.2)  
121(39.8) 43(14.1) 140(46.1)  
70(22.7) 44(14.3) 194(62.9)  
2
tested by χ test. The level of significance was set at  
P <0.05.  
27(9.0)  
88(29.1) 187(61.9)  
Do you think too much antibiotic is bad for your  
child? (n=305)  
194(63.6) 53(17.4) 58(19.0)  
ST = sore-throat  
Results  
Characteristics of the respondents  
More respondents from the secondary and tertiary levels  
of education 59.0% and 56.6% respectively compared to  
Of the 320 questionnaires administered, 11 respondents  
declined the interview giving a response rate of 96.6%, a  
total of 309 respondents were thus studied. The respon-  
dents consisted of 264 (85.4%) mothers and 45 (14.6%)  
fathers. The respondents were aged between 20 and 64  
years with a median age of 32.0 years. The respondents  
aged <30 years were 125(40.4%), 30 – 39 years were  
2
0.6% with primary level of education would not re-  
quest for antibiotic , P <0.001. Table 2.  
Older respondents 71(52.2%) in the 30 – 39 years age  
group and 22(57.9%)40 years compared to younger  
respondents aged 30 years 40(33.9%) would see an-  
other doctor to get an antibiotic prescription, P = 0.011.  
Table 3. There was no significant gender difference in  
the responses to questions on attitude to antibiotic pre-  
scription. table 4.  
1
42(46.0%) and 42(13.6%) were 40 years or older. The  
majority of parents 177(57.3%) had tertiary level of edu-  
cation, while 108(34.9%) and 24(7.8%) had secondary  
and primary levels of education respectively. Most of  
the respondents 139 (45.0%) were from high SEC, 87  
(
28.1%) and 83 (26.9%) were from middle and low  
SECs respectively. Of the 309 parents, 204 (66.0%) had  
1
00  
Table 2: Parents’ attitude to antibiotic prescription for sore-  
throat by level of education  
conducted in Port Harcourt, Nigeria where 83.7% of  
children < 5 years were prescribed antibiotics for upper  
respiratory tract infections . The value in this study is  
9
Questions  
Responses  
n = number of responses  
LOE  
Agree Not sure Disagree P value  
however higher than the 29% reported from a Malaysian  
1
0
Would you request for antibiotic for  
your child with ST? (n= 304)  
study . The higher proportion in the present study may  
stem from the belief that most people in the locality be-  
lieve that antibiotic is required for most illnesses, this is  
Pri  
7(11.1) 43(68.3) 13(20.6)  
Sec 24(22.9) 19(18.1) 62(59.0) <0.001  
Ter 56(32.0) 20(11.4) 99(56.6)  
1
1
Satisfied with a doctor who does not  
more so as it is readily available over the counter . Over  
half of the respondents believe that the sore-throat will  
resolve without antibiotics. This was in contrast with  
their belief that sore-throat should be treated with antibi-  
otics.  
prescribe antibiotic for ST? (n=306) Pri  
9(37.5)  
3(12.5) 12(50.0)  
Sec 47(43.9) 21(19.6) 39(36.4) 0.63  
Ter 73(41.7) 26(14.9) 76(43.4)  
Would you see another doctor to get  
antibiotic for ST? (n = 304)  
Pri  
11(45.8) 6(25.0) 7(29.2)  
Sec  
Ter  
39(37.1) 19(18.1) 47(44.8) 0.053  
90(51.4) 18(10.3) 67(38.3)  
Would you change your doctor for not  
prescribing antibiotic for ST?(308)  
Pri  
Sec  
Ter 112(64.0) 28(16.0) 35(20.0)  
16(66.7) 3(12.5)  
64(59.8) 13(12.1) 30(28.0) 0.057  
5(20.8)  
Also in contrast with their belief in the spontaneous  
resolution of sore-throat is that over half of the respon-  
dents would request for antibiotic from their physician  
in this study. Moreover majority of the respondents did  
not think that the receipt of antibiotics for sore-throat in  
their children constituted over prescription. The number  
of respondents requesting for antibiotic in0 this study is  
See a doctor to prevent potential  
complication from ST? (n=305)  
Pri  
4(17.4) 1(4.3)  
18(78.3)  
90(84.9) 0.36  
156(88.6)  
Sec  
Ter 12(6.8)  
8(7.5)  
8(7.5)  
8(4.5)  
LOE = Level of education; Pri, Sec and Ter = primary, secondary and  
tertiary levels of education respectively.  
1
higher than the 28% in a Malaysian study and the 24%  
1
2
in a Greek study where the parents thought that antibi-  
otic was part of the treatment for upper respiratory tract  
infection. The lower value in the Greek study is because  
of the better education of the parents with regards to  
upper respiratory tract infections and their willingness to  
Table 3: Parents’ attitude to antibiotic prescription for sore-  
throat by age group  
Questions  
Responses  
n = number of responses  
Age (yrs) Agree Not sure Disagree P value  
Would you request for antibiotic  
for your child with ST? (n= 304)  
<30  
31(26.5) 10(8.5) 76(65.0)  
12  
follow their physicians’ instructions . In this study, the  
3
0-39 47(34.3) 25(18.2) 65(47.5) 0.031  
40  
8(20.5)  
6(15.4) 25(64.1)  
more educated parents were less likely to request for  
antibiotic, suggesting that education may have influ-  
enced their disposition to request for antibiotic.  
Satisfied with a doctor who does not  
prescribe antibiotic for ST? (n=306) <30  
56(47.5)  
19(16.1) 43(36.4)  
18(13.1) 65(47.4) 0.15  
10(26.3) 13(34.2)  
30-39 54(39.4)  
40 15(39.5)  
Would you see another doctor to  
get antibiotic for ST? (n = 304)  
<30 40(33.9) 17(14.4) 61(51.7)  
0-39 71(52.2) 20(14.7) 45(33.1) 0.011  
40 22(57.9) 5(13.2) 11(28.9)  
Would you change your doctor for not  
prescribing antibiotic for ST?(308) <30  
Although most upper respiratory tract infections includ-  
ing sore-throat are caused mostly by viruses, the fear of  
3
possible complication of group  
A
streptococcal  
59(66.7) 21(12.5)  
0-39 99(59.8) 14(12.1)  
37(20.8)  
pharyngitis may have encouraged treatment with anti-  
bioitics for all cases of sore-throat in our environment  
where rheumatic heart disease is endemic. This is  
against the situation in western countries where rheu-  
matic heart disease is almost non-existent and it is easier  
to promote non-prescription of antibiotics for sore-  
throat. However in the face of the growing antibiotic  
resistance and the attendant complications, prescription  
of antibiotics for all cases of sore-throat will not be justi-  
fied even in our environment. Clearly, measures to re-  
duce antibiotic prescription for sore-throat without un-  
dulling exposing a possible case of bacterial pharyngitis  
to complications of rheumatic fever and acute glomeru-  
lonephritis need to be put in place in the country.  
3
24(28.0) 0.006  
6(15.4)  
40  
28(71.8) 5(12.8)  
See a doctor to prevent potential  
complication from ST? (n=305)  
<30  
0-39 12(8.8)  
40 7(17.9)  
4(3.4)  
7(6.0)  
5(3.7)  
3(7.7)  
106(90.6)  
119(87.5) 0.36  
29(74.4)  
3
Table 4: Parents’ attitude to antibiotic prescription for sore-  
throat by gender of parent  
Questions  
n = number of responses  
Responses  
Parents Agree Not sure Disagree P value  
Would you request for antibiotic for  
your child with ST? (n= 304)  
Father 10(22.2) 9(20.0) 26(57.8)  
Mother 77(29.7) 34(13.2) 148(57.1) 0.36  
Satisfied with a doctor who does not  
prescribe antibiotic for ST? (n=306) Father 21(47.7) 3(6.8) 20(45.5)  
Mother 108(41.2) 47(18.0) 107(40.8) 0.18  
Would you see another doctor to get  
antibiotic for ST? (n = 304)  
Father 25(56.8) 5(11.4) 14(31.8)  
Mother 115(44.2) 38(14.6) 107(41.2) 0.30  
Waiting for microbiological confirmation of bacterial  
infection where the facility is available, may be imprac-  
ticable as decision on the need for or against antibiotics  
prescription have to be taken empirically at the first visit  
since the patient may not make the second visit 48 hours  
later. The use of a clinical decision rule by the physi-  
Would you change your doctor for not  
prescribing antibiotic for ST?(308) Father 33(73.4) 6(13.3)  
6(13.3)  
Mother 159(60.9) 38(14.6) 64(24.5) 0.21  
See a doctor to prevent potential  
complication from ST? (n=305)  
Father 4(8.9) 2(4.4)  
39(86.7)  
Mother 20(7.7) 15(5.8) 225(86.5) 0.91  
1
3
cian such as the modified Centor criteria , will reduce  
significantly the number of sore-throat cases for which  
1
4
antibiotics are needlessly prescribed for . The clinical  
rules are usually locale specific and since there is none  
in Nigeria yet, use of the available rule in our setting  
may produce incorrect results. Use of rapid diagnostic  
testing for group A streptococcus may be the way for-  
Discussion  
In this study, almost 70% of the respondents believe that  
every child with sore throat should have antibiotics. This  
high proportion is consistent with the finding in a study  
1
01  
ward in our environment since it does not require high  
level of technical skill to perform and results are avail-  
able within a short time. There is a need for a national  
policy on antibiotic treatment of upper respiratory tract  
infections including sore-throat that provides a more  
rational antibiotic treatment of upper respiratory tract  
infections. This recommendation has been made in ear-  
lier paper on the subject . The populace should also be  
educated about such policy and thus reduce demand for  
antibiotics.  
further emphasizes the need for education of our parents  
about the causes of upper respiratory tract infections,  
indication for antibiotic prescription and the danger of  
indiscriminate antibiotic prescriptions. The irrational  
parental demand for antibiotics may stem from a desire  
for their child to get better faster. Parental education on  
the aetiology and natural history of sore-throat may  
change the extant attitudinal disposition. Recommending  
other alternatives such as home fluids, soothing reme-  
dies may relieve demands for antibiotics.  
1
4
It would appear that lack of knowledge or fear of com-  
plications is also engendering other negative behaviours.  
For instance, almost a quarter of the respondents in this  
study would change their children’s physician if they did  
not prescribe an antibiotic. Such attitude puts undue  
pressure on the physicians, especially the private practi-  
tioner, who in a bid to retain their clientele might be  
pressured to prescribe unnecessary antibiotics for every  
sore throat. This attitude of unrealistic parental expecta-  
tion contributing to inappropriate antibiotic prescription  
In this study, the modality for data collection was by  
interviewer administered questionnaire. This was to  
ensure that the meaning of questions was similarly pre-  
sented to the respondents irrespective of the level of  
education and that all the questions were responded too.  
In a self-administered questionnaire, the understanding  
of the questions might be influenced by level of educa-  
tion of the respondents and as such influence the  
responses.  
1
5
has been reported by another worker . The actual re-  
quest for antibiotic prescription for nonspecific upper  
respiratory tract infection had been reported to have in-  
fluenced 49%1o6f physicians’ prescription of antibiotic in  
another study.  
Conclusion  
In conclusion, the knowledge that most sore-throat are  
5
In this study, 42% of the respondents would not be satis-  
fied with a doctor who does not prescribe antibiotics for  
sore throat. This perception of satisfaction linked with  
physicians’ prescription of antibiotic is different from  
findings in a study from a western country where par-  
ents satisfaction correlated with time spent with physi-  
cians rather than on prescription of antibiotics . The  
attitude expressed by the western parents may stem from  
better understanding of the disease process, the need for  
and danger of inappropriate antibiotic prescription. This  
self-limiting because of their viral aetiology, did not  
seem to affect the disposition of the parents studied to  
antibiotics use. Studies are needed to understand the  
reasons for the incongruence in belief and practice. We  
recommend the development of a national policy on  
antibiotic treatment of upper respiratory tract infection  
including sore-throat and the health education of parents  
on aetiology of sore-throat and irrational antibiotic use.  
Such education should be emphasized in the individual  
parent where the child has a sore-throat.  
1
7
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